New PrEP Study: SeroPrEP

Posted August 31, 2023

Colleagues at UCSF are conducting a study called SeroPrEP to characterize new HIV infections among persons using long-acting injectable cabotegravir (CAB-LA) or oral PrEP.

SeroPrEP is an observational (non-interventional) study that aims to evaluate causes of HIV acquisition on CAB-LA or oral PrEP via sensitive assays for ARV resistance, drug levels/pharmacokinetics (PK), and diagnostics; and assess subsequent HIV treatment outcomes on ART. The study is funded by the National Institutes of Health.

Participant eligibility criteria include:

  • One or more HIV tests suggesting that HIV-1 infection has occurred (e.g. Ag/Ab, RNA)
  • Use/receipt of CAB-LA in the past 18 months or oral PrEP in the past 3 months
  • Age >= 18 years

The study involves:

  • A brief online participant survey and e-consent
  • A brief online clinician survey
  • Collection of blood, urine, and small scalp hair samples
  • A behavioral questionnaire
  • Follow-up for up to 12 months in the study to assess ART outcomes 

SeroPrEP enrolls participants from all 50 U.S. states and Puerto Rico. Patients who enroll in the study receive a $50 gift card for each study visit.

Enrollment information can be found on our study website. See below for a Study Flyer, Study Slide and Dear Provider letter – please circulate these to your colleagues who may have patients eligible for the study.

Click below to download the Sero PrEP

Flyer for SeroPrEP Study

Click below to download the SeroPrEP Dear Doctor Letter:

SeroPrEP Dear Doctor Letter

Click below to download the SeroPrEP Overview Slide:

SeroPrEP Overview Slide


Please let the SeroPrEP study team know if it would be possible to include their study information in your newsletters/network communications, or to include their study slide in trainings related to long-acting HIV prevention, PrEP, or HIV testing.

Contact Information:

The SeroPrEP team

Catherine Koss, MD; Urvi Parikh, PhD;

Monica Gandhi, MD, MPH; Lisa Georgetti Gomez, MSPH | | (415) 539-5688

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